The United States on Thursday imposed sanctions on seven Iranian officials over the shutdown of internet access and the crackdown on peaceful protesters.

The US Treasury Department in a statement said it imposed sanctions on Iran's minister of interior, Ahmad Vahidi; Communications Minister Eisa Zarepour; and Vahid Mohammad Naser Majid, the head of the Iranian Cyber Police, among others.

"The United States condemns the Iranian government’s Internet shutdown and continued violent suppression of peaceful protest and will not hesitate to target those who direct and support such actions," Under Secretary of the Treasury Brian Nelson said in the statement.

The nationwide unrest sparked by Mahsa Amini's death in hijab police custody has spiraled into the biggest challenge to Iran's clerical leaders in years, with protesters calling for the downfall of the Islamic Republic founded in 1979.

Rights groups say thousands have been arrested and hundreds injured in the crackdown waged by security forces including the Basij, a militia affiliated with Iran's Revolutionary Guards. Rights groups put the death toll at over 150.

The United States last month imposed sanctions on Iran's morality police over allegations of abuse of Iranian women, saying it held the unit responsible for the death of Amini, an Iranian Kurd who died after being detained in Tehran on Sept. 13 for "inappropriate attire."

Authorities have reported numerous deaths among the security forces, accusing foreign adversaries, including the United States, of meddling to destabilize Iran, without providing any tangible evidence.

Reporting by Reuters